Brewery Profile

Zymos Brewing

In Littleton’s beer scene, a visitor finds Zymos Brewing operating as a neighborhood taproom with variety at the center of the experience. The defining feature is the breadth of the draft list: 26 taps, giving guests room to move across different styles rather than committing to a single house identity. The setting is built for sampling and repeat visits, with beer drinkers able to compare lighter, crisper pours against darker or fuller-bodied options in the same stop. Non-alcoholic choices are also part of the offering, which makes the taproom more flexible for mixed groups. For travelers exploring breweries around the south Denver area, it reads as a local stop focused on choice and community rather than spectacle.

Visitors to Colorado breweries often look for range: something refreshing after time outdoors, a classic lager or ale for an easy first pour, and perhaps a darker beer when the weather or mood calls for it. Zymos fits that pattern by keeping a wide tap lineup that can include styles from crisp lagers to robust stouts. That variety is useful in a region where brewery visits are often social and informal, with groups arriving with different preferences. Someone interested in exploring several styles can build an easy tasting path, while another guest can settle on a familiar pour. The presence of non-alcoholic options also helps make the stop workable for drivers, non-drinkers, or anyone pacing a longer day.

Because specific details such as food service, outdoor seating, events, reservations, and parking are not established here, the taproom is the place to confirm the day’s practical details and current pours. The beer list is likely to be the main reason to visit, especially for guests who value a broad draft board and want to see what is flowing that day. With 26 taps, availability may change, so checking in at the bar is the most reliable way to learn what styles are on offer. Travelers planning a Littleton brewery stop should treat Zymos Brewing as a taproom-centered visit: come prepared to browse the board, ask about the current lineup, and choose based on the day’s selection.

Nestled in the heart of Littleton, Zymos Brewing is the quintessential neighborhood taproom, built on variety and community spirit. With an impressive 26 taps flowing, they offer a vast spectrum of expertly crafted beers alongside a thoughtful selection of non-alcoholic options, ensuring every palate finds its perfect pour. It's the ideal Colorado spot to settle in and explore diverse styles, from crisp lagers to robust stouts.

Website available

5180 S Lowell Blvd, Littleton, Colorado, 80123

Phone: 720 664 5280

Website: http://zymosbrewing.com

Upcoming Events

Upcoming public events currently attached to this brewery.

  • Sunday Magic

    Oct 10, 2026

    Experience magical entertainment every Sunday evening at the brewery along with your favorite brews.

  • Irish Session Night - open to all

    Oct 11, 2026

    Join us for an open Irish music session night, welcoming all to enjoy traditional tunes and good company.

  • Trivia @ Zymos

    Oct 12, 2026

    Participate in our weekly trivia night for a fun and challenging evening with friends and craft beer.

  • Karaoke Night!

    Oct 12, 2026

    Show off your singing talent or cheer on others during our Karaoke Night at the brewery. A fun evening for all!

  • Open Mic Night, Hosted by The Talented Mr. Ripley

    Oct 12, 2026

    Showcase your talents or enjoy others during our open mic night hosted at the brewery.

  • Open Mic Hosted by Steve (The Magpie)

    Oct 13, 2026

    Showcase your talents or enjoy local artists at our weekly open mic night hosted by Steve.

  • Board Game Exchange

    Oct 13, 2026

    Bring your favorite board games to exchange and enjoy with new friends at Zymos Brewing.

  • Noice Choice Trivia

    Oct 15, 2026

    Join Noice Choice Trivia with prizes for top teams and beer shots for fun categories. Enjoy themed trivia every third Thursday.

  • Not Your Mother's Book Club

    Oct 15, 2026

    Join a book club for engaging discussions paired with great craft beer. Share and enjoy new book experiences.

  • Queer Craft Night with Littleton Q+

    Oct 27, 2026

    A social evening celebrating the queer community with craft beer and fun activities. Join us for a welcoming night.

Frequently Asked Questions

Where is Zymos Brewing located?
Zymos Brewing is located at 5180 S Lowell Blvd, Littleton, Colorado, 80123. Use the map and directions on this page to plan your visit.
What are Zymos Brewing's hours?
Taproom hours are not posted to Beer.Social. Call 720 664 5280 to confirm before visiting.
How can I learn more about Zymos Brewing?
Visit http://zymosbrewing.com for the brewery's own information about beers, events, and operations. Beer.Social aggregates public data and visitor-facing details to help with planning a stop.