Brewery Profile

WISEACRE Brewing Company HQ

Downtown Memphis gives this headquarters facility a setting that is closely tied to the city’s visitor traffic, music history, and nightlife. At the intersection of BB King Boulevard and Butler Avenue, near the historic Beale Street district, WISEACRE Brewing Company HQ functions as both a production site and a public taproom. A visitor walking in finds a large, art-forward room rather than a small tasting counter, with the brewery’s beer program presented across thirty taps. The lineup focuses mainly on year-round core styles, so the experience is built around getting a broad view of what the brewery regularly makes rather than chasing only limited releases. Behind the public-facing side, the facility is equipped with a 50-barrel Braukon brewing system and a high-speed packaging line that can process 250 cans per minute, giving the taproom a direct connection to a working production brewery.

Travelers in Memphis often look for stops that can fit around music venues, sports, restaurants, and downtown sightseeing, and a brewery visit here can serve that role without requiring a detour far from the city’s central activity. The beer list offers enough range for visitors who want to compare several styles, while the emphasis on core offerings makes it useful for anyone trying the brewery for the first time. For people exploring regional beer, the value is not just in finding a single flagship pour, but in seeing how a Memphis brewery presents its regular lineup in its home setting. The on-site pizza kitchen, Little Bettie, also makes the stop more flexible: it can work as a quick drink, a casual meal, or a longer visit with a group.

The taproom is open seven days a week for drinking on site and for packaged beer sales, so it can fit into most travel schedules. Because the draft list can change, the taproom is the place to confirm the day’s pours and any current packaged options. Visitors should also check the brewery’s current calendar if they want to catch one of its regular community events, such as weekly trivia nights or happy hours. The combination of a large taproom, food from Little Bettie, packaged beer to go, and a downtown address near Beale Street makes the HQ a practical stop for travelers who want a Memphis brewery experience without separating it from the rest of a downtown itinerary.

WISEACRE Brewing Company operates its headquarters facility in downtown Memphis, Tennessee, situated at the intersection of BB King Boulevard and Butler Avenue, near the historic Beale Street district. This location houses a large, art-forward taproom offering a selection of thirty different beers on tap, focusing primarily on the brewery's year-round core styles. The facility utilizes a 50-barrel Braukon brewing system for production, supported by a high-speed packaging line capable of processing 250 cans per minute. Food service is provided by Little Bettie, an on-site pizza kitchen. The taproom is open seven days a week for both on-site consumption and packaged beer sales, and it regularly hosts community events such as weekly trivia nights and happy hours.

Website available

398 S B.B. King Blvd, Memphis, TN 38126, USA, Memphis, Tennessee, 38126

Phone: (901) 881-2615

Website: https://wiseacrebrew.com/location/hq-taproom/

Hours: Open today from 12pm - 9pm

Popular Beers

A quick look at notable pours currently tied to WISEACRE Brewing Company HQ.

Beer Styles at WISEACRE Brewing Company HQ

WISEACRE Brewing Company HQ brews across a range of styles. The current lineup includes American Pilsner, Premium Lager, Coffee Milk Stout, Chelada with Salt and Lime, Helles Lager, IPA, Hazy IPA, Oatmeal Stout, Mexican Style Amber Lager, Belgian Wit, Barleywine, and Dry Hopped Pale Ale. Specific pours rotate over time — check the taproom board on the day of your visit for what is currently available on tap.

Upcoming Events

Upcoming public events currently attached to this brewery.

  • Sporcle Music Trivia Night

    Jul 7, 2026

    Tuesday Sporcle Music Trivia Night at WISEACRE Brewing Company HQ, listed alongside Tuesday $5 pint specials.

  • Wednesday Trivia Night

    Jul 7, 2026

    Weekly Wednesday trivia at WISEACRE Brewing Company HQ during Downtown Brew Hop 2026 specials/features.

Frequently Asked Questions

Where is WISEACRE Brewing Company HQ located?
WISEACRE Brewing Company HQ is located at 398 S B.B. King Blvd, Memphis, TN 38126, USA, Memphis, Tennessee, 38126. Use the map and directions on this page to plan your visit.
What are WISEACRE Brewing Company HQ's hours?
Current hours are: Open today from 12pm - 9pm. Hours can change on holidays and during private events — call ahead if your visit is time-sensitive.
How can I learn more about WISEACRE Brewing Company HQ?
Visit https://wiseacrebrew.com/location/hq-taproom/ for the brewery's own information about beers, events, and operations. Beer.Social aggregates public data and visitor-facing details to help with planning a stop.