Brewery Profile

The Depot Craft Brewery Distillery

Inside a three-story brick former railway headquarters, The Depot Craft Brewery & Distillery gives Reno visitors a beer stop with a strong sense of place. The building at 325 East 4th Street was constructed in 1910 for the Nevada-California-Oregon Railway, and that history shapes the first impression as much as the brewing and distilling do. In a city with multiple craft-beverage options, this one stands out for occupying a structure tied to the region’s working past rather than a purpose-built modern taproom. A visitor walking in should expect the experience to be centered on the building, the production of beer and spirits, and the contrast between historic surroundings and current craft methods.

Travelers exploring beer in northern Nevada often look for a range of styles, from familiar traditional pours to more experimental releases, and this brewery-distillery fits that kind of itinerary. Its stated approach combines traditional methods with newer craft processes, with attention to local sourcing and quality ingredients. Because it produces both beer and spirits, it can appeal to visitors who are comparing breweries, distilleries, or stops that do both under one roof. The site’s railway background also adds context: the original Nevada-California-Oregon Railway served ranchers and farmers by moving livestock, wool, hay, and grain along a 238-mile route to Lakeview, Oregon. That agricultural and transportation history gives the visit more regional grounding than a drink list alone would provide.

For planning purposes, the address is the key detail: 325 East 4th Street in Reno. Specific taproom amenities, food options, tours, seating arrangements, and current hours are not confirmed here, so the taproom is the place to confirm the day’s pours and any available spirits. Visitors interested in particular beer styles or experimental offerings should check directly before going, since rotating production can change what is available. The main reason to include The Depot Craft Brewery & Distillery on a Reno visit is straightforward: it offers beer and spirits in a documented 1910 railway building, with operations aimed at both traditional and exploratory craft production.

Located at 325 East 4th Street in Reno, Nevada, The Depot Craft Brewery & Distillery occupies a three-story brick building constructed in 1910 as the headquarters for the Nevada-California-Oregon Railway. This railway historically served local ranchers and farmers by transporting livestock, wool, hay, and grain across a 238-mile route to Lakeview, Oregon. The brewery and distillery combine traditional methods and innovative craft processes within this historic structure. Their operations emphasize local sourcing and quality ingredients, aiming to create both traditional and experimental beer and spirits. The facility supports a range of production activities designed to explore and refine their craft offerings.

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325 E 4th St, Reno, Nevada, 89512-3313

Phone: 7757374330

Website: http://www.thedepotreno.com

Upcoming Events

Upcoming public events currently attached to this brewery.

  • Brewery Tours

    Oct 24, 2026

    Guided tours through The Depot Craft Brewery Distillery are offered every Saturday. Visitors can learn about the brewing and distilling process and explore the grounds. The averag…

  • Open Mic Poetry at Shim's

    Oct 26, 2026

    Every Monday night from 6:00-8:00 PM, join us at Shim's for Open Mic Poetry sessions welcoming local poets and enthusiasts to share their work and enjoy an inspiring evening.

Frequently Asked Questions

Where is The Depot Craft Brewery Distillery located?
The Depot Craft Brewery Distillery is located at 325 E 4th St, Reno, Nevada, 89512-3313. Use the map and directions on this page to plan your visit.
What are The Depot Craft Brewery Distillery's hours?
Taproom hours are not posted to Beer.Social. Call 7757374330 to confirm before visiting.
How can I learn more about The Depot Craft Brewery Distillery?
Visit http://www.thedepotreno.com for the brewery's own information about beers, events, and operations. Beer.Social aggregates public data and visitor-facing details to help with planning a stop.